Drug Use Utilization of N-Acetylcysteine (NAC) in COVID-19 Patients

at Santa Elisabeth General Hospital Purwokerto

Faradina Qorina Nadzif, Masita Wulandari Suryoputri, Heny Ekowati

Departement of Pharmacy, Faculty of Health Sciences, Jenderal Soedirman University

Jl. Dr. Suparno, Karangwangkal, Purwokerto, 53123, Indonesia

Corresponding author: Faradina Qorina Nadzif, Phone : +62-813-93340027, e-mail : faradina.nadzif@mhs.unsoed.ac.id

ABSTRACT

Introduction : Infection of SARS-CoV-2 or COVID-19 is associated with an imbalance of oxidants and antioxidants which lead to inflammation and tissue damage. One of the therapy for COVID-19 is N-acetylcysteine (NAC). This study aimed to identify drug use utilization of NAC as antioxidant in COVID-19 patient in Santa Elisabeth General Hospital, Purwokerto.

Method : This study was an observational study with a descriptive  cross-sectional design. Data was collected retrospectively based on medical records of COVID-19 patients hospitalized at Santa Elisabeth General Hospital between September 2020 to March 2021. Data in this study were analysed descriptively.

Result :. The results showed that the percentage of COVID-19 patients at Santa Elisabeth General Hospital was 48.51% male and 51.85% female. There were 86 patients (85.14%) administered with NAC, the recovery rate was 83.65% and the death rate was 16.35%.

Conclusion : This study indicated that the administration of N-acetylcysteine (NAC) in COVID-19 at Santa Elisabeth General Hospital was 85.14% and the recovery rate 85.65%.

Keyword : N-acetylcysteine ​​(NAC), COVID-19, Santa Elisabeth General Hospital.