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Drug Use Utilization of Antiviral in COVID-19 Patients at Ajibarang Regional General HospitalIndah Jaya Cahyani, Heny Ekowati, Masita Wulandari SuryoputriDepartement of Pharmacy, Faculty of Health Sciences, Jenderal Soedirman UniversityJl. Dr. Suparno, Karangwangkal, Purwokerto 53123, IndonesiaCorresponding author: Indah Jaya Cahyani, Mailing address : Tangerang, Indonesia, Phone : +62-857-02137042, email : Indah.cahyani@mhs.unsoed.ac.idABSTRACTBackground: Coronavirus Disease (COVID-19) is a respiratory disease caused by SARS-CoV-2. One of the therapy for COVID-19 is antiviral drug. Oseltamivir and Avigan are widely used as therapy for COVID-19. This study aimed to evaluate the antiviral used and the most dominant administered to COVID-19 patients.Methods: This research is an observational study with purposive sampling. Data were collected retrospectively based on medical records of hospitalized COVID-19 patients at Ajibarang Hospital between April 2020-March 2021. All data were analysed descriptively.Results: Based on the analysis of 56 COVID-19 patients, the characteristics of the research subjects were obtained : age, gender, and antiviral drugs used in COVID-19 patients. The highest age category was 18-85 years with a percentage of 40.31%, the gender were 51.26% male and 48.73% female. The most antiviral administered to patients were Avigan 42 patients (75%), Oseltamivir 14 patients (25%).Conclusion: The result showed that the most dominant antiviral therapy in Ajibarang Hospital from April 2020 to March 2021 was Avigan with a percentage of 75%.Keywords: Drug utilization, antiviral, COVID-19, Ajibarang Hospital