Background: Interprofessional Education (IPE) is an integrated education concept to improve collaboration capabilities initiated by WHO. Interprofessional collaboration practices are expected to be able to minimize medication errors also to improve quality of care and patient safety. This study aims to analyze integratively research on the readiness of nursing students in inter-professional collaboration practice.

Methods: A systematic literature review search of four database of indexed international journals, namely Science Direct, PubMed, ProQuest, and EBSCO was conducted. Inclusion criteria used for the search includes original research, publication time 2016-2020, English-written, and accessible in full text. Studies were included if they have keywords of knowledge, perception, interprofessional collaboration, and nursing student. Research articles were critically appraised and analyzed through a table containing title, author, year, methodology, results, and recommendations. Lastly, data were synthesised narratively to address the study aims.

Results: There were 24 research articles that met the criteria. IPE can be implemented in the form of simulations, elective courses, and workshops integrated with the curriculum. Important components of IPE are roles, responsibilities, cooperation, interpersonal skills, critical thinking, problem solving, care management, values ​and ethics, communication, group dynamics, and leadership. The results showed an improve of knowledge, attitudes, perceptions, skills, readiness, and competency of nursing students after the implementation of IPE.

Conclusion: IPE simulation prepares nursing students to excel interprofessional collaboration practices. IPE can be integrated in the higher education health curriculum. IPE applications can be carried out in academic, clinical, and community settings.