The COVID-19 pandemic situation makes people need to use masks. Therefore, the amount of mask trash is high, and thus, destroying the pathogens on the masks, including Coronavirus or officially known as SARS-CoV-2, before disposing of them into a bin is necessary. Heat from UVC lamps can kill the pathogens on the masks and reduce the budget for destroying the masks due to being infected biomedical waste. The UVC light can kill the pathogens at the DNA and RNA levels. The aim of this research study was to develop a surgical mask trash can (SMT) to prevent transmission for the nursing students at Princess of Naradhiwas University. The SMT was developed by installing the UVC light in a trash can and using the heat from cellular cells. The heat from the UVC light is higher than 60 - 75 °C, by which the pathogens are killed. The 30 nursing students were recruited to provide their opinions and levels of satisfaction with using the SMT. The statistics used in the research were descriptive statistics, frequency, percentage, mean and standard deviation. From the results, it was found that the highest levels of satisfaction for using the SMT were in the items of “The SMT is suitable for the current situation” ( = 3.9, SD = 0.31) and “It is recommended that the SMT be put everywhere in the university.” However, there is an expectation that further research on the SMT can be conducted by testing the effectiveness of the killing of the pathogens living on the masks in the SMT and testing the temperature range in the trash can.